Diabetes doesn't significantly affect TKR outcomes, report finds

Burgeoning research suggests that patients with diabetes are not more prone to infection, deep vein thrombosis or other complications following total knee replacement (TKR) than their non-diabetic counterparts.

Analysts looked to 40,000 Kaiser Permanente TKR patient records when attempting to decipher whether or not glycemic control had any effect on the outcome of the particular surgery.

The findings were as follows:

All information courtesy of Kaiser Permanente. Presentation by PhysBizTech.

The report also noted:

  • The rates of deep infection, deep vein thrombosis and pulmonary embolism were low, and comparable in the controlled and uncontrolled diabetic groups to the non-diabetic group.
  • Uncontrolled diabetics (12.5 percent) did not appear to be associated with an increased risk of myocardial infarction or rehospitalization.
  • Controlled diabetics (6.2 percent) had a slightly greater percentage of revisions (1.7 percent) compared to uncontrolled diabetics (1.2 percent).

"This current study suggests that patients with diabetes who have higher glucose levels may not be at greater risk of poor surgical outcomes," remarked Annette L. Adams, PhD, MPH, of the Kaiser Permanente Southern California Department of Research & Evaluation, in a prepared statement. "There appear to be other factors at play, and patients and their providers need to consider multiple factors, including but not limited to diabetes status, as they make decisions about whether to have this surgery."

The study is to be published in the upcoming March issue of the Journal of Bone and Joint Surgery.


Image courtesy of Nevit Dilmen via Creative Commons licensing.