Nutritional deficiencies have been linked to adverse neuronal functions and neuronal plasticity in patients with attention deficit hyperactivity disorder (ADHD). What’s more, researchers from the Riordan Clinic identified behavioral impacts as a possible result of the deficits.
The latest study attributes shortages of fatty acids (EPA, DHA), methionine, zinc and selenium to metabolic difficulties and emotional strain in those aged two to 25 years old with ADHD.
“According to our data, the metabolic correction of ADHD by supplementation can ameliorate ADHD symptoms. Eighty percent of children who were treated from several weeks to 1-2 years, demonstrated improvement of metabolic stress level, measured by pyrrole test. For these patients, the levels of EPA were increased and the omega-6/omega-3 ratio was improved," said Nina Mikirova, MD, director of research at the Riordan Clinic, in a news release.
Analysts combed over and tracked patient histories for 10 years, performing laboratory tests on 116 of the patients diagnosed with ADHD as a means to compare the distribution of fatty acids, essential metals and metabolic stress levels within that given subject. Moreover, toxic metal concentration presence in conjunction with essential metal levels was examined and considered in the report’s conclusion.
“Putting all data together, it was demonstrated that after consumption of a combination of fatty acids as well as magnesium and zinc, amino acids, vitamins and probiotics, most subjects had a considerable reduction in markers of metabolic stress and reported less emotional problems,” the report said.
Despite the promising connections, Mikirova and the remaining members of the report team champion the movement to conduct more study on integrative metabolic correction therapy in relation to ADHD management.
“In this study, it was demonstrated that metabolic correction of biochemical disturbances using essential fatty acids, amino acids, and minerals can improve fatty acid profiles and metabolic stress levels,” the authors concluded. “These disturbances or variations from reference values have been associated with behavior typical of ADHD. Further studies need to be conducted with integrative metabolic correction therapy to determine its value in the management of ADHD.”
The study was published in the latest edition of the journal Functional Foods in Health and Disease. Find the report in its entirety here.
Image courtesy of Nicolas P. Rougier via Creative Commons licensing.